Search results for "genetics [Mutation]"

showing 10 items of 3026 documents

New records of phytoseiid mites from Italy, with description of a new species and a redescription of other two (Parasitiformes, Phytoseiidae)

2020

The Italian phytoseiid fauna consists of 91 valid species. Eighteen of them were described as new species from materials collected in various Italian localities. In the present paper we report nine new records from the Italian fauna and describe the new species, Neoseiulus mediterraneus belonging to the subfamily Amblyseiinae. Complementary descriptions of two rare species, namely: Typhlodromus (Anthoseius) singularis and Typhlodromus (Typhlodromus) knisleyi, were also added.

0106 biological sciencesPhytoseiidaeArthropodaFaunaAacriformes010607 zoologyZoologyAcariformes[SDV.BID.SPT]Life Sciences [q-bio]/Biodiversity/Systematics Phylogenetics and taxonomy01 natural sciencesdescriptionsArachnidaAnimaliaAcariPhytoseiidaeAcariTaxonomynew speciesDescriptions Italy Mesostigmata New species PhytoseiidaebiologyParasitiformesBiodiversitybiology.organism_classificationAcariformes[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology010602 entomologySettore AGR/11 - Entomologia Generale E ApplicataItalyTyphlodromusInsect ScienceMesostigmataMesostigmataNeoseiulus
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Plants in the UK flower a month earlier under recent warming.

2022

Global temperatures are rising at an unprecedented rate, but environmental responses are often difficult to recognize and quantify. Long-term observations of plant phenology, the annually recurring sequence of plant developmental stages, can provide sensitive measures of climate change and important information for ecosystem services. Here, we present 419 354 recordings of the first flowering date from 406 plant species in the UK between 1753 and 2019 CE. Community-wide first flowering advanced by almost one month on average when comparing all observations before and after 1986 ( p < 0.0001). The mean first flowering time is 6 days earlier in southern than northern sites, 5 days earlier…

General Immunology and MicrobiologyEcologyBritish IslesTemperaturefood and beveragesplant phenologyGeneral MedicineFlowersPlantsGeneral Biochemistry Genetics and Molecular BiologyUnited Kingdomecosystem serviceclimate changeResearch articlesFOS: Biological sciencescitizen scienceSeasonsGeneral Agricultural and Biological Scienceswoodland trustEcosystemGeneral Environmental Science
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Effects of foliar application of glycine betaine and chitosan on Puccinellia distans (Jacq.) Pari, subjected to salt stress.

2019

Introduction:Using brackish water for irrigation may expose turfgrasses to salinity stress.Employing the best treatments to maintain high-quality turfs under saline conditions is animportant requirement for turfgrass management.Methods:We tested the response of ahalophyte grass,Puccinellia distans, to irrigation with saline solutions and to foliarapplication of two osmoprotectants, such as glycine betaine (GB) or chitosan (CH). Plantswere grown in pots under controlled conditions and irrigated with 200 mM or 600 mM ofNaCl solutions. The response to salinity treatments and osmoprotectant application wasevaluated after 90 days by measuring leaffiring, leaf density, shoot length and biomass, r…

IrrigationBrackish waterbiologyChemistryturfgrass glycine betaine chitosan Puccinellia distans salt stressbiology.organism_classificationGeneral Biochemistry Genetics and Molecular BiologySalinityHorticultureWater potentialHalophyteSettore BIO/03 - Botanica Ambientale E ApplicataShootSettore BIO/04 - Fisiologia VegetaleOsmoprotectantPuccinellia distansGeneral Agricultural and Biological SciencesBiologia futura
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Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma

2018

Recurrent mutations in chromatin modifiers are specifically prevalent in adolescent or adult patients with Sonic hedgehog-associated medulloblastoma (SHH MB). Here, we report that mutations in the acetyltransferase CREBBP have opposing effects during the development of the cerebellum, the primary site of origin of SHH MB. Our data reveal that loss of Crebbp in cerebellar granule neuron progenitors (GNPs) during embryonic development of mice compromises GNP development, in part by downregulation of brain-derived neurotrophic factor (Bdnf). Interestingly, concomitant cerebellar hypoplasia was also observed in patients with Rubinstein-Taybi syndrome, a congenital disorder caused by germline mu…

0301 basic medicineCerebellumCrebbp protein mousemetabolism [Cerebellar Neoplasms]acetyltransferase; cerebellum; CREBBP; development; Rubinstein-Taybi syndrome; SHH medulloblastomagenetics [Hedgehog Proteins]MiceNeurotrophic factorsmetabolism [CREB-Binding Protein]Mice KnockoutNeuronsRubinstein-Taybi Syndromepathology [Rubinstein-Taybi Syndrome]CREBBPCREB-Binding ProteinPhenotypegenetics [CREB-Binding Protein]3. Good healthpathology [Cerebellar Neoplasms]acetyltransferasePhenotypemedicine.anatomical_structuregenetics [Rubinstein-Taybi Syndrome]Femalemetabolism [Hedgehog Proteins]Signal TransductionSHH medulloblastomaAdultcerebellumBiologyGeneral Biochemistry Genetics and Molecular BiologyCREBBP; Rubinstein-Taybi syndrome; SHH medulloblastoma; acetyltransferase; cerebellum; development.03 medical and health sciencesGermline mutationAcetyltransferasesmetabolism [Medulloblastoma]medicineAnimalsHumansgenetics [Cerebellar Neoplasms]Hedgehog Proteinsddc:610Cerebellar NeoplasmsdevelopmentMolecular BiologyMedulloblastomaRubinstein–Taybi syndromegenetics [Medulloblastoma]metabolism [Rubinstein-Taybi Syndrome]pathology [Medulloblastoma]Cell Biologymedicine.disease030104 developmental biologyMutationphysiology [CREB-Binding Protein]Cancer researchSHH protein humanCerebellar hypoplasia (non-human)metabolism [Acetyltransferases]CREBBP protein humanMedulloblastomaDevelopmental BiologyCongenital disorderDevelopmental Cell
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About the Influences of Some Major Biotic Drivers on the Population Dynamics in Host-parasite Systems: Interpretative Lessons from an Extended Nichol…

2020

Population dynamics within host-parasite systems in insects is governed by a series of factors, both endogenous and exogenous. Among them, five factors may be considered as major drivers: the respective inherent rates of increase of the host and of the parasite, the level of resource available to the host, the respective immigration rates of the host and of the parasite. While only the first two (the inherent rates of increase of host and parasite) are considered in the original Nicholson and Bailey model, an extended version of the model includes also the other three parameters, thus providing a broader (although still schematic) approach to the host-parasite population dynamics. A brief a…

education.field_of_studyHost (biology)EcologyThaumetopoea pityocampaPopulationParasite hostingBiologyGeneral Agricultural and Biological ScienceseducationNicholson–Bailey modelPine processionary mothGeneral Biochemistry Genetics and Molecular BiologyAnnual Research & Review in Biology
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Development and localization of microsatellite markers for the sibling species Chironomus riparius and Chironomus piger (Diptera: Chironomidae)

2006

Five variable microsatellite loci are reported for the nonbiting midge species Chironomus riparius and Chironomus piger. All loci show considerable intraspecific variation and species-specific alleles, which allow to discriminate among the two closely related species and their interspecific hybrids, and to estimate genetic diversity within and between populations. Additionally, the loci were localized on C. riparius polytene chromosomes to verify their single copy status and investigate possible chromosomal linkage. The described markers are used in different studies with regard to population and ecological genetics and evolutionary ecotoxicology of Chironomus.

Chironomus ripariusGeneticsGenetic diversityeducation.field_of_studyPolytene chromosomeEcologybiologyved/biologyved/biology.organism_classification_rank.speciesPopulationbiology.organism_classificationBiochemistryGeneral Biochemistry Genetics and Molecular BiologyIntraspecific competitionstomatognathic systemEvolutionary biologyMidgeMicrosatelliteChironomuseducationMolecular Ecology Notes
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ESR study of the liposome membrane physical parameters in the heating-cooling cycles.

1998

Abstract Changes of dynamic and structural parameters of egg yolk lecithin (EYL) liposome mem­branes in the heating-cooling cycles have been studied using the E S R spin probe method. The investigations were conducted in the range of temperatures from -18 °C to +60 °C. It has been found that in the range of temperatures -15 °C to +45 °C in both the heating and the cooling run the spectroscopic parameters changed practically along the same curve (re­versible changes). However, after exceeding this range of temperatures one of the parameters (partition coefficient of the spin probe 2,2,6,6 -tetramethylpiperidine -1-oxyl; TEMPO) changed along a closed curve, showing the phenomenon of thermal h…

Range (particle radiation)Liposomefood.ingredientMaterials scienceHot TemperatureAnalytical chemistryElectron Spin Resonance SpectroscopyActive surfaceLecithinEgg YolkGeneral Biochemistry Genetics and Molecular BiologySpin probePartition coefficientCold TemperatureCyclic N-OxidesfoodMembraneLiposomesPhosphatidylcholinesMoleculeThermodynamicsSpin LabelsZeitschrift fur Naturforschung. C, Journal of biosciences
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Bile Duct Warmer in Hepatic Cryosurgery—A Pig Liver Model

1998

Freezing of the common bile duct resulted in injury, stenosis, or perforation of the bile duct in a dog model. Biliary cutaneous fistulas and bile leaks are reported as complications of hepatic cryosurgery in man. In an ex vivo pig liver model we compared freezing close to the bile duct with and without warming the bile duct with warmed saline solution via an inserted catheter ("bile duct warmer"). The recorded temperatures at the outer wall of the bile duct were -50 degrees C after 10 min of freezing without and 5. 8 degrees C with the use of the warmer (P0.001, two-way ANOVA). The bile duct warmer system may be a simple and inexpensive device in reducing perioperative morbidity after hepa…

medicine.medical_specialtyHot TemperatureSwinemedicine.medical_treatmentPerforation (oil well)Sodium ChlorideCryosurgeryModels Biologicaldigestive systemGastroenterologyGeneral Biochemistry Genetics and Molecular BiologyCryosurgeryCatheterizationDogsPostoperative ComplicationsInternal medicinemedicineAnimalsHumansSalineCommon bile ductBile ductbusiness.industryLiver NeoplasmsGeneral Medicinemedicine.diseaseStenosisCathetermedicine.anatomical_structureLiverEvaluation Studies as TopicBiliary tractBile DuctsGeneral Agricultural and Biological SciencesbusinessCryobiology
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Two phosphonodehydrotripeptides: Boc0–Gly1–Δ(Z)Phe2–α‐Abu3PO3Me2 and Boc0–Gly1–Δ(Z)Phe2–α‐Nva3PO3Et2

2012

The present paper reports the crystal structures of two short phosphonotripeptides (one in two crystal forms) containing one ΔPhe (dehydrophenylalanine) residue, namely dimethyl (3-{[tert-butoxycarbonylglycyl-α,β-(Z)-dehydrophenylalanyl]amino}propyl)phosphonate, Boc0–Gly1–Δ(Z)Phe2–α-Abu3PO3Me2, C21H32N3O7P, (I), and diethyl (4-{[tert-butoxycarbonylglycyl-α,β-(Z)-dehydrophenylalanyl]amino}butyl)phosphonate, Boc0–Gly1–Δ(Z)Phe2–α-Nva3PO3Et2, as the propan-2-ol monosolvate 0.122-hydrate, C24H38N3O7P·C3H8O·0.122H2O, (II), and the ethanol monosolvate 0.076-hydrate, C24H38N3O7P·C2H6O·0.076H2O, (III). The crystals of (II) and (III) are isomorphous but differ in the type of solvent. The phosphono gr…

chemistry.chemical_classificationEthanolHydrogen bondStereochemistryHydrogen moleculeGeneral MedicineCrystal structureGeneral Biochemistry Genetics and Molecular BiologyAmino acidCrystalSolventchemistry.chemical_compoundResidue (chemistry)chemistryActa Crystallographica Section C-Crystal Structure Communications
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Differential in vitro Anti-HIV Activity of Natural Lignans

1990

Abstract Two naturally occurring lignanolides, isolated from the tropical climbing shrub Ipomoea cairica, (-)-arctigen in and (-)-trachelogen in , were found to inhibit strongly replication of human immunodeficiency virus type 1 (HIV-1; strain HTLV-III B) in vitro. At a concentration of 0.5 (μм , (-)-arctigenin and (-)-trachelogenin inhibited the expression of HIV-1 proteins p 17 and p24 by 80 -90 % and 60 -70 % , respectively. The reverse transcriptase activity in the cul­ture fluids was reduced by 80 -90 % when the cells (HTLV-III B/H 9) were cultivated in the presence of 0.5 μм (-)-arctigen in or 1 μм (-)-trachelogenin . At the same concentrations, the formation of syncytia in the HTLV-I…

Antiviral AgentsLigninLignansGeneral Biochemistry Genetics and Molecular BiologyCell LineMiceStructure-Activity RelationshipViral Proteinschemistry.chemical_compoundAnimalsHumansLeukemia L5178Lignanchemistry.chemical_classificationbiologyTopoisomeraseHIVvirus diseasesDNA topoisomerase II activityMolecular biologyReverse transcriptaseIn vitroDNA Topoisomerases Type IIEnzymechemistryViral replicationCell cultureHIV-1biology.proteinCell DivisionPlasmidsZeitschrift für Naturforschung C
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